17 Science Street is located in Park Hills, Missouri, within the broader Farmington–Park Hills commercial and employment corridor of St. Francois County. The property provides convenient access to U.S. Highway 67, offering direct connectivity throughout the region and south toward Farmington. The surrounding area is seeing significant new investment, including a planned Amazon last-mile distribution center in Park Hills representing an estimated $30–$40 million investment and approximately 80–100 jobs. Additional industrial investment includes Reworld’s new Park Hills operation, bringing more than $7 million in investment to an approximately 150,000-square-foot facility.
Just south along Highway 67, construction is also underway on Farmington Crossings, a new 316,000+ square-foot open-air shopping center planned to feature Target, Academy Sports + Outdoors, Burlington, and additional retail space. The development represents a significant addition to the region’s retail base and is designed to draw consumers from throughout the broader Southeast Missouri trade area. Mineral Area College provides another important local anchor, with continued investment in workforce and technical training facilities. Together, expanding retail, new employment centers, established institutions, and convenient Highway 67 access position 17 Science Street within an increasingly active commercial and investment corridor in St. Francois County.